Dota 2 Wiki
Main Article: Runes

Additional Information[]

Rune of Regeneration prev
  • Power Runes
    • Power runes start spawning at the 6:00 minute mark, and then every 2 minutes (8:00, 10:00, 12:00, etc.)
    • They spawn at one of the rune spots within the river, which is randomly chosen.
    • If a Power Rune is not picked up before the next one spawns, it disappears.
    • Power Runes never repeat a rune within a cycle, meaning if a specific rune spawned, it cannot spawn again until all other Power Runes have spawned as well.
    • The same Power Rune cannot spawn twice in a row, meaning the first rune of the next cycle cannot be the same as last rune of the previous cycle.


No Target
Regenerates health and mana to maximum. If taking damage from an enemy hero, the regeneration rate is lowered to 1% HP/MP per second.
Max Health as Health Regen per Second: 6%
Max Mana as Mana Regen per Second: 6%
Health Regen (Damaged): 1%
Mana Regen (Damaged): 1%
Duration: 30
Damage Regen Reduction Duration: 3
Modifiers [?]
Regeneration Rune buff icon

Buff icon

  • Can regenerate up to 180% of a unit's max health and max mana over its full duration.
    • If continuously taking player damage, can regenerate up to 30% of a unit's max health and mana.
  • Can fully regenerate a unit's health and mana within 16.67 seconds.
  • The buff disappears once the hero is at full health and mana.
  • Damage greater than 0 from any player (including allies and self) or Roshan icon Roshan reduces the regeneration to 1% for 3 seconds.
    • Does not get reduced by damage flagged as HP Removal.
  • Successive buffs of multiple Regeneration Runes do not stack but refresh the duration instead.